MANUFACTURING PROCESS OF FORMULATION HAVING IMPROVED CONTENT UNIFORMITY

The present invention offers the manufacturing method of the solid formulation wherein the standard deviation of the active ingredient content in the solid formulation becomes 5% or less by mixing the excipients which have a median particle size of 15 or more times, preferably 20 times or more to th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ICHIO, Shunji, MASHIMO, Akira
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention offers the manufacturing method of the solid formulation wherein the standard deviation of the active ingredient content in the solid formulation becomes 5% or less by mixing the excipients which have a median particle size of 15 or more times, preferably 20 times or more to the median particle size of an active ingredient.