De Novo Design of Allosteric Proteins

Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.

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Bibliographische Detailangaben
Hauptverfasser: Raman, Srivatsan, Church, George M, Taylor, Noah D
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.