APPARATUS FOR HIGH THROUGHPUT CONTINUOUS DROPLET ELECTROPORATION FOR DELIVERY OF A MATERIAL, AND A METHOD FOR DROPLET ELECTROPORATION USING THE SAME

An electroporation device is disclosed, which includes a first tubular electrode including a first inlet and a first outlet; an aqueous solution supply connected to the first tubular electrode and configured for supplying an aqueous solution to the first tubular electrode and for allowing a droplet...

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Bibliographische Detailangaben
Hauptverfasser: IM, Do Jin, Yoo, Byeong Sun, AHN, Myung Mo
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:An electroporation device is disclosed, which includes a first tubular electrode including a first inlet and a first outlet; an aqueous solution supply connected to the first tubular electrode and configured for supplying an aqueous solution to the first tubular electrode and for allowing a droplet of the aqueous solution to be discharged from the first outlet of the first tubular electrode, the aqueous solution contains a cell and a delivery target substance; a second tubular electrode including a second inlet and a second outlet, wherein the second inlet is spaced away from the first outlet at a spacing corresponding to a size of a portion of the droplet; a power supply for applying a voltage to the electrodes for electroporation of the cell in the droplet; and a droplet sucking unit connected to the second electrode and configured for allowing the droplet to be sucked into the second electrode.