EXTRUDED DEPOT FORM FOR CONTINUING ACTIVE SUBSTANCE RELEASE

EXTRUDED DEPOT FORM FOR CONTINUING ACTIVE SUBSTANCE RELEASE

The invention relates to an extruded depot form for a continuing active substance release, comprising at least one active substance and at least two compounds of the class of substances which can be broken down by lipases. The at least two compounds comprise a low-melting compound and a high-melting...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: PARTENHAUSER, Alexandra
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention relates to an extruded depot form for a continuing active substance release, comprising at least one active substance and at least two compounds of the class of substances which can be broken down by lipases. The at least two compounds comprise a low-melting compound and a high-melting compound, and the ratio of the low-melting compound to the high-melting compound ranges from 1:9 to 9:1. The depot form also optionally comprises at least one auxiliary agent for modulating the active substance release, wherein b), or optionally b) and c), constitute at least 60 wt. % of the dry weight of the depot form.