SEPARATION DEVICES, ASSOCIATED METHODS, AND SYSTEMS

A system for isolating a target molecule from a bioprocess fluid includes a single-use disposable separation device having a plurality of perimeter-bonded layers defining one or more mesofluidic channels of the separation device, wherein each layer includes a biocompatible polymer material, wherein...

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Bibliographische Detailangaben
Hauptverfasser: Gettings, Rachel Marie, Castle, Jason William, Galligan, Craig Patrick, Morton, Christine Angela, Misner, Matthew Jeremiah, Hale, Jared Timothy, Kvam, Erik Leeming, De, Anindya Kanti, Pizzi, Vincent Francis
Format: Patent
Sprache:eng
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Zusammenfassung:A system for isolating a target molecule from a bioprocess fluid includes a single-use disposable separation device having a plurality of perimeter-bonded layers defining one or more mesofluidic channels of the separation device, wherein each layer includes a biocompatible polymer material, wherein the separation device is configured to separate at least a portion of particles from the bioprocess fluid to generate a substantially clarified bioprocess fluid, and a chromatography system fluidically coupled at the outflow of the separation device in a configuration for further processing the clarified bioprocess fluid.