TRANSDERMAL THERAPEUTIC SYSTEM
A transdermal therapeutic system including: a support layer of a flexible tape; an adhesive layer that is permeable and laminated in a surface of the support layer; a drug that is transdermally absorbable and stored in each of a plurality of storage cavities in the surface of at least the support la...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A transdermal therapeutic system including: a support layer of a flexible tape; an adhesive layer that is permeable and laminated in a surface of the support layer; a drug that is transdermally absorbable and stored in each of a plurality of storage cavities in the surface of at least the support layer among the support layer and the adhesive layer; and a liner layer detachably laminated in an adhesive surface of the adhesive layer, wherein when a polyether ether ketone resin film having low irritancy is used as the support layer, the polyether ether ketone resin film is used as a sample, and an intradermal reaction test is carried out by using an extract extracted under predetermined conditions in a physiological saline or sesame oil, a difference in average scores of an extract administration site and a blank extract administration site is 1.0 or less in any of extraction media. |
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