OPTOFLUIDIC DEVICE AND METHOD FOR DETECTING CIRCULATING TUMOUR CELLS

The present invention relates to a microfluidic device for the detection of circulating tumour cells (CTCs) in a fluid sample. The invention also relates to an in vitro method for the detection and/or quantification of circulating tumour cells (CTCs) in a fluid sample. Further, the invention relates...

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Bibliographische Detailangaben
Hauptverfasser:	Alvarez-Puebla, Ramon Angel, Nazarenus, Moritz Julian, Pedrol, Eric, Diaz, Francisco, Fernandez, Eduardo Garcia-Rico, Massons, Jaume, Garcia Algar, Manuel
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a microfluidic device for the detection of circulating tumour cells (CTCs) in a fluid sample. The invention also relates to an in vitro method for the detection and/or quantification of circulating tumour cells (CTCs) in a fluid sample. Further, the invention relates to in vitro methods for (a) diagnosing a tumour and/or metastasis in a subject, and (b) determining the prognosis of a subject suffering from a tumour and/or metastasis. Finally, the invention refers to a kit comprising (a) a microfluidic device according to the first aspect of the invention, and (b) labelled probes targeting a first CTCs surface marker and, optionally, at least a second CTCs surface marker.