METHODS OF INDUCING RESPONSIVENESS TO ANTI-ANGIOGENIC AGENT

METHODS OF INDUCING RESPONSIVENESS TO ANTI-ANGIOGENIC AGENT

The invention provides methods of inducing or improving responsiveness to a VEGF antagonist to a subject or a subject population comprising administering an adenovirus comprising a nucleic acid construct comprising a F AS-chimera gene operably linked to an endothelial cell-specific promoter and admi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FEIGE, Erez, BREITBART, Eyal, SHER, Naamit, LEUBITZ, Andrea Rachel
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention provides methods of inducing or improving responsiveness to a VEGF antagonist to a subject or a subject population comprising administering an adenovirus comprising a nucleic acid construct comprising a F AS-chimera gene operably linked to an endothelial cell-specific promoter and administering the VEGF antagonist.