CARBOHYDRATE CONTENT OF CTLA4 MOLECULES

The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Brownell, Dean Woodrow, Donaldson, Robert, Kirkley, David Henry, Vanden Boom, Thomas James, Bramhall, Elizabeth A, Schrimsher, Jeffrey, Bates, Ronald Charles, Thammana, Pallaiah, Leister, Kirk J, Didio, David Michael, Tabor, John Malcolm, Whitehead, Joyce Patricia, Velayudhan, Ajoy, Schaefer, Eugene J, Haggerty, Helen Gray, Russell, Reb J, Smolin, David Edward, Flesher, Alan R, Tay, Lee K
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION TRANSPORTING
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Beschreibung
Zusammenfassung:	The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.