SCALABLE MAGNETOMECHANICAL SCHEMES AND DEVICES FOR REMOTE CONTROL OF MECHANOSENSITIVE CELLS

The present invention provides novel methods and devices for the remote stimulation of mechanosensitive cells using magnetically-induced forces that are significantly lower in magnitude than currently possible. Novel biocompatible anisotropic magnetic nanodiscs allow for remote magnetomechanical sti...

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Bibliographische Detailangaben
Hauptverfasser:	Anikeeva, Polina Olegovna, Senko, Alexander William, Reddy, Pooja D, Gregurec, Danijela
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ELECTROTHERAPY ENZYMOLOGY HUMAN NECESSITIES HYGIENE MAGNETOTHERAPY MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS RADIATION THERAPY SPIRITS ULTRASOUND THERAPY VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides novel methods and devices for the remote stimulation of mechanosensitive cells using magnetically-induced forces that are significantly lower in magnitude than currently possible. Novel biocompatible anisotropic magnetic nanodiscs allow for remote magnetomechanical stimulation of cell signaling in mechanosensitive cells at scale without compromising cell viability. The methods and devices of the present invention allow for investigation of mechanoreception in general, and in particular, for studies in neurological, neurodegenerative; and neuromuscular diseases.