SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION

Provided herein are pre-formulations forming a biocompatible hydrogel polymer comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally a therapeutic agent and/or viscosity enhancer. In some embodiments, the biocompatible hydro...

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Bibliographische Detailangaben
Hauptverfasser: WAN, Paul YuJen, CHOI, YEON S, ASKARI, Syed H
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein are pre-formulations forming a biocompatible hydrogel polymer comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally a therapeutic agent and/or viscosity enhancer. In some embodiments, the biocompatible hydrogel polymer covers a wound in a mammal and adheres to the surrounding skin tissue. In other embodiments, the hydrogel polymer is delivered into a joint space to treat joint disease or navicular disease.