PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF

PROCESS FOR PREPARATION OF ERIBULIN AND INTERMEDIATES THEREOF

The present application relate to process for preparation of tetrahydrofuran compound of formula II, 4-Methylene tetrahydrofuran compound of formula V and tetrahydropyran compound of formula IX which are useful as intermediates for the preparation of halichondrin B analogues such as Eribulin or its...

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Hauptverfasser: SARVESH, Kumar, WARREN, Sarah Ann, PENUMANDLA, Raja gopal, ORUGANTI, Srinivas, DAHANUKAR, Vilas Hareshwar, MANDAL, Amit Kumar, EDA, Vishnu Vardhana Vema Reddy, FOX, Martin Edward, LLOYD, Michael Charles, RAO, Pallavi, PALVAI, Prapulla Kumar, MEEK, Graham Andrew, DAVIDSON, Robert Wen Ming, BASU, Debjit
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present application relate to process for preparation of tetrahydrofuran compound of formula II, 4-Methylene tetrahydrofuran compound of formula V and tetrahydropyran compound of formula IX which are useful as intermediates for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts.