METHOD FOR PREPARING HYALURONIC ACID DERMAL FILLERS, DERMAL FILLERS OBTAINED THEREBY AND THEIR USE

The present invention generally relates to the field of hyaluronic acid (HA) dermal fillers, and more specifically to methods for preparing crosslinked HA-based compositions in the form of a gel comprising high-temperature dialysis and/or crosslinking in the presence of phosphate and an alkaline met...

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Bibliographische Detailangaben
Hauptverfasser: HAGEDORN, Nadine, BELKOVI, Lubin, EL-BANNA, Radia, STRAGIES, Roland
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention generally relates to the field of hyaluronic acid (HA) dermal fillers, and more specifically to methods for preparing crosslinked HA-based compositions in the form of a gel comprising high-temperature dialysis and/or crosslinking in the presence of phosphate and an alkaline metal halide salt. The present invention further relates to crosslinked HA-based gel compositions prepared by said methods and their use as dermal fillers in aesthetic applications such as wrinkle treatments.