ANTIBODY TO PROGRAMMED CELL DEATH 1 (PD-1) AND USE THEREOF

Disclosed are an antibody to human programmed cell death 1 (PD-1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, an isolated cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, a...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Si Hyung, Kim, Soo Young, Kim, Hye-Nan, Cho, Young-Gyu, Lim, Jung Chae, Youn, Jin Chul, Park, Jae Eun, Park, Bum-chan, Park, Young Woo, Lee, Hyun Mi, Lee, Hyun Kyung
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are an antibody to human programmed cell death 1 (PD-1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, an isolated cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, and a composition for preventing or treating cancer containing the same. The novel antibody binding to PD-1 or an antigen-binding fragment thereof can bind to PD-1 and inhibit the activity of PD-1, thus being useful for the development of immunotherapeutic agents for various diseases associated with PD-1.