NANOPARTICLE DIAGNOSTIC AND METHODS FOR TREATING DISEASE

The present invention relates to the use of in vivo contrast agents in medical imaging in order to diagnose and treat disease, and to monitor and assess disease progression following treatment with a nanoparticle therapeutic agent comprising an active pharmaceutical agent. The present invention also...

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Bibliographische Detailangaben
Hauptverfasser: Bilodeau, Mark T, Dupont, Michelle, Lim Soo, Patrick, Shinde, Rajesh R, Dunbar, Craig A, Iwicki, Mark, Kadiyala, Sudhakar, Alargova, Rossitza G
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to the use of in vivo contrast agents in medical imaging in order to diagnose and treat disease, and to monitor and assess disease progression following treatment with a nanoparticle therapeutic agent comprising an active pharmaceutical agent. The present invention also relates to modulating nanoparticle tumor concentration by modulating the PEG density of the nanoparticles.