GENE EDITING, IDENTIFYING EDITED CELLS, AND KITS FOR USE THEREIN

Provided are methods of identifying a cell that has been edited with a gene editing reagent. Also provided are methods of selecting a clone of a cell that has been identified as an edited cell containing a desired edit, as well as methods of gene editing that include such selecting of an edited clon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Morell Fernández, Montserrat, Martin, Patrick, Farmer, Andrew Alan, Haugwitz, Michael, Smith, Baz
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided are methods of identifying a cell that has been edited with a gene editing reagent. Also provided are methods of selecting a clone of a cell that has been identified as an edited cell containing a desired edit, as well as methods of gene editing that include such selecting of an edited clone. Methods of assessing the efficacy of gene editing reagents and methods employing a gene editing reagent efficacy assessment are also provided. The instant disclosure further provides kits for use in practicing the subject methods.