MODIFIED FRT RECOMBINATION SITE LIBRARIES AND METHODS OF USE

Methods and compositions using populations of randomized mod fie FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT re...

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Bibliographische Detailangaben
Hauptverfasser: Gordon-Kamm, William J, Tao, Yumin, Bidney, Dennis, Lyznik, Leszek A
Format: Patent
Sprache:eng
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Zusammenfassung:Methods and compositions using populations of randomized mod fie FRT recombination sites to identify, isolate and/or characterize modified FRT recombination sites are provided. Kits comprising the library populations of FRT sites are also provided, as are methods to make a library of modified FRT recombination sites. The recombinogenic modified FRT recombination sites can be employed in a variety of methods for targeted recombination of polynucleotides of interest.