COMPOSITIONS AND METHODS FOR SELECTIVE GI TRACT DELIVERY

A composition is hereby provided. The present composition comprises one or more micro-sized particles in the form of a core-shell. The core comprises an active agent and ingredients subject to pH-triggered dissolution, enzymatically-degradable ingredients and/or water-insoluble ingredients. The shel...

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Bibliographische Detailangaben
Hauptverfasser: ROZNER, Dorit, SHACHAR, Gilad, BARZILAY, Amir
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A composition is hereby provided. The present composition comprises one or more micro-sized particles in the form of a core-shell. The core comprises an active agent and ingredients subject to pH-triggered dissolution, enzymatically-degradable ingredients and/or water-insoluble ingredients. The shell comprises one or more ingredients being characterized as enteric ingredients, enzymatically-degradable, and as water-insoluble ingredients. The particles may be dispersed in a liquid or other non-dry composition.