SOLVENT-CAST MICROPROTRUSION ARRAYS CONTAINING ACTIVE INGREDIENT

In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution ato...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WORSHAM, Robert Wade, KLEMM, Andrew Richard, KLEMM, Steven Richard, CHEN, Guohua, TRAUTMAN, Joseph C, BAYRAMOV, Danir, BOWERS, Danny Lee, SINGH, Parminder
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:In an aspect of the invention, an array of microprotrusions is formed by providing a mold with cavities corresponding to the negative of the microprotrusions, casting atop the mold a first solution comprising a biocompatible material and a solvent, removing the solvent, casting a second solution atop the first cast solution, removing the solvent from the second solution, and demolding the resulting array from the mold. The first solution preferably contains an active ingredient.