METHOD TO TREAT ASTHMA AND AIRWAY ALLERGY USING CYCLO TYROSINE-VALINE AND RELATED COMPOUNDS
The present invention provides a method to treat asthma and airway allergy by administering the dipeptide cyclo tyrosine-valine or a related cyclodipeptide compound to a subject in need thereof. Cyclo tyrosine-valine or the related cyclodipeptide compound reduces Th2 cell activation, airway hyperres...
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| creator | Lin, Chuan-Sheng Chen, Yu-Li Lai, Hsin-Chih Wu, Tsung-Ru Liau, Jian-Ching Antig, Luis Dominick B Chiu, Chen-Yaw Martel, Jan Hsieh, Pei-Wen Chang, Chih-Jung Lu, Chia-Chen Ko, Yun-Fei Young, John D Ojcius, David Marcelo |
| description | The present invention provides a method to treat asthma and airway allergy by administering the dipeptide cyclo tyrosine-valine or a related cyclodipeptide compound to a subject in need thereof. Cyclo tyrosine-valine or the related cyclodipeptide compound reduces Th2 cell activation, airway hyperresponsiveness, accumulation of immune cells in bronchoalveolar fluid, and allergen-specific antibody production in an animal or human subject. The compound can therefore be used to treat asthma and airway allergy. |
| format | Patent |
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Cyclo tyrosine-valine or the related cyclodipeptide compound reduces Th2 cell activation, airway hyperresponsiveness, accumulation of immune cells in bronchoalveolar fluid, and allergen-specific antibody production in an animal or human subject. 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Cyclo tyrosine-valine or the related cyclodipeptide compound reduces Th2 cell activation, airway hyperresponsiveness, accumulation of immune cells in bronchoalveolar fluid, and allergen-specific antibody production in an animal or human subject. The compound can therefore be used to treat asthma and airway allergy.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | METHOD TO TREAT ASTHMA AND AIRWAY ALLERGY USING CYCLO TYROSINE-VALINE AND RELATED COMPOUNDS |
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