CHROMATOGRAPHY METHOD FOR QUANTIFYING A NON-IONIC SURFACTANT IN A COMPOSITION COMPRISING THE NON-IONIC SURFACTANT AND A POLYPEPTIDE

The invention provides methods for quantifying a non-ionic surfactant in a composition comprising a polypeptide and the non-ionic surfactant, where the quantification exhibits reduced interference between the non-ionic surfactant and the polypeptide. Also provided are methods where the composition f...

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Hauptverfasser: BEARDSLEY, Richard L, CHINN, Michael S, MONTTI, Mary
Format: Patent
Sprache:eng
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Zusammenfassung:The invention provides methods for quantifying a non-ionic surfactant in a composition comprising a polypeptide and the non-ionic surfactant, where the quantification exhibits reduced interference between the non-ionic surfactant and the polypeptide. Also provided are methods where the composition further includes N-acetyl tryptophan, and the quantification exhibits reduced interference between the non-ionic surfactant, the polypeptide, and N-acetyl tryptophan.