METHODS FOR IDENTIFYING AND MODULATING IMMUNE PHENOTYPES

The present invention provides tools and methods for the systematic analysis of genetic interactions in immune cells. The present invention provides tools and methods for modulating immune cell phenotypes and compositions, combinatorial probing of cellular circuits, for dissecting cellular circuitry...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHALEK, Alexander K, YOSEF, Nir, GAYO, Enrique Martin, COLE, Michael B, KOLB, Kellie E, OUYANG, Zhengyu, YU, Xu
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides tools and methods for the systematic analysis of genetic interactions in immune cells. The present invention provides tools and methods for modulating immune cell phenotypes and compositions, combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.