GENETICALLY ENGINEERED CELLS AND METHODS OF MAKING THE SAME

Provided are CRIS PR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequence, and applications thereof in connection with cancer immunotherapy comprising adoptive transfer of engineered T cells or T cell...

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Bibliographische Detailangaben
Hauptverfasser: SATHER, Blythe, JONES, Jon, SALMON, Ruth, WELSTEAD, G. Grant, NYE, Chris, RUBIO, Eugenio Marco, BUMCROT, David A, MAEDER, Morgan L, FRIEDLAND, Ari E
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are CRIS PR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequence, and applications thereof in connection with cancer immunotherapy comprising adoptive transfer of engineered T cells or T cell precursors.