METHOD FOR PRODUCING AFFINITY SEPARATION MATRIX, AND AFFINITY SEPARATION MATRIX

A method for producing an affinity separation matrix includes immobilizing a κ chain variable region-binding peptide on a water-insoluble carrier through a terminal cysteine residue of the κ chain variable region-binding peptide. The cysteine residue is located at an N-terminal or a C-terminal of th...

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Bibliographische Detailangaben
Hauptverfasser: Yoshida, Shinichi, Murata, Dai
Format: Patent
Sprache:eng
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Zusammenfassung:A method for producing an affinity separation matrix includes immobilizing a κ chain variable region-binding peptide on a water-insoluble carrier through a terminal cysteine residue of the κ chain variable region-binding peptide. The cysteine residue is located at an N-terminal or a C-terminal of the κ chain variable region-binding peptide. The κ chain variable region-binding peptide is a ligand having an affinity for a κ chain variable region. The affinity separation matrix includes the ligand and the water-insoluble carrier.