ANTI-CXCR3 ANTIBODIES AND METHODS OF USE THEREOF

ANTI-CXCR3 ANTIBODIES AND METHODS OF USE THEREOF

The present disclosure provides anti-CXCR3 antibodies and methods of using the antibodies to diagnose and/or treat CXCR3-associated disorders such as diabetes mellitus type I (T1D), particularly new-onset T1D. In certain embodiments, disclosed herein are CXCR3 neutralizing antibodies.

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Bibliographische Detailangaben
Hauptverfasser: Chu, Ruiyin, Pinckney, Jason Robert, Masterjohn, Elizabeth, Youd, Michele, Lodie, Tracey, Carter, Karen B, Connors, Timothy D, Tedstone, Jennifer
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure provides anti-CXCR3 antibodies and methods of using the antibodies to diagnose and/or treat CXCR3-associated disorders such as diabetes mellitus type I (T1D), particularly new-onset T1D. In certain embodiments, disclosed herein are CXCR3 neutralizing antibodies.