Processes for the Preparation of Veliparib and Intermediates Thereof

Processes for the Preparation of Veliparib and Intermediates Thereof

The present invention provides processes for the preparation of Veliparib (1), as well as intermediates useful in the preparation thereof. In particular, processes are provided for the production of the compound of Formula (3), or a salt thereof, and cyclization to afford Veliparib (1). (see formula...

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Hauptverfasser: Milnes, Kaarina K, Bodhuri, Prabhudas, Gorin, Boris, Weeratunga, Gamini, Green, Melanie R. A
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator Milnes, Kaarina K
Bodhuri, Prabhudas
Gorin, Boris
Weeratunga, Gamini
Green, Melanie R. A
description The present invention provides processes for the preparation of Veliparib (1), as well as intermediates useful in the preparation thereof. In particular, processes are provided for the production of the compound of Formula (3), or a salt thereof, and cyclization to afford Veliparib (1). (see formula 3)
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Processes for the Preparation of Veliparib and Intermediates Thereof
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