Processes for the Preparation of Veliparib and Intermediates Thereof

Processes for the Preparation of Veliparib and Intermediates Thereof

The present invention provides processes for the preparation of Veliparib (1), as well as intermediates useful in the preparation thereof. In particular, processes are provided for the production of the compound of Formula (3), or a salt thereof, and cyclization to afford Veliparib (1). (see formula...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Milnes, Kaarina K, Bodhuri, Prabhudas, Gorin, Boris, Weeratunga, Gamini, Green, Melanie R. A
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides processes for the preparation of Veliparib (1), as well as intermediates useful in the preparation thereof. In particular, processes are provided for the production of the compound of Formula (3), or a salt thereof, and cyclization to afford Veliparib (1). (see formula 3)