Loading Platform For Three-Dimensional Tissue Engineered Scaffolds

A scaffold-stretching system includes at least one stretchable loading chamber configured to support a scaffold material and a supply of cells, such as human skin substitute cells, and is configured to allow for cultivation of a cellular three-dimensional scaffold; and a mechanical loading system is...

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Bibliographische Detailangaben
Hauptverfasser: Elsaadany, Mostafa, Subramanian, Gayathri, Yildirim-Ayan, Eda
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A scaffold-stretching system includes at least one stretchable loading chamber configured to support a scaffold material and a supply of cells, such as human skin substitute cells, and is configured to allow for cultivation of a cellular three-dimensional scaffold; and a mechanical loading system is configured for application of cyclic and static uniaxial tensile mechanical loading on the cellular three-dimensional scaffold, and is configured to mimic the in vivo environment of musculoskeletal, cardiovascular, and other tissues that experience uniaxial strains.