DERIVATIVES OF PYRROLOIMIDAZOLE OR ANALOGUES THEREOF WHICH ARE USEFUL FOR THE TREATMENT OF INTER ALIA CANCER

DERIVATIVES OF PYRROLOIMIDAZOLE OR ANALOGUES THEREOF WHICH ARE USEFUL FOR THE TREATMENT OF INTER ALIA CANCER

The invention further relates to the process of their preparation, pharmaceutical composition and their use in modulating the activity of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO). The compounds of the invention can be used alone or in combination for the treatment of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KULATHINGAL, Jayanarayan, JANRAO, Ravindra Ashok, KALHAPURE, Vijay Keshav, GURJAR, Mukund Keshav, ROYCHOWDHURY, Abhijit, LEKKALA, Rammohan Reddy, URUNKAR, Ganesh Devidas, GULLAPALLI, Srinivas, KHALADKAR, Tushar Pandurang, SAWARGAVE, Sangmeshwar Prabhakar
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention further relates to the process of their preparation, pharmaceutical composition and their use in modulating the activity of indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO). The compounds of the invention can be used alone or in combination for the treatment of conditions that benefits from the inhibition of tryptophan degradation.