CRYSTALLINE AND AMORPHOUS FORMS OF CARFILZOMIB

CRYSTALLINE AND AMORPHOUS FORMS OF CARFILZOMIB

The present disclosure provides crystalline carfilzomib form M1 and a process for the preparation thereof. Further disclosed are processes for the preparation of amorphous carfilzomib using crystalline form M1 as a starting material. The present disclosure also relates to an improved process for the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sangvikar, Yogesh, Gore, Vinayak, Gharat, Sushant, Shukla, Vinay Kumar, Kokane, Dattatrey
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure provides crystalline carfilzomib form M1 and a process for the preparation thereof. Further disclosed are processes for the preparation of amorphous carfilzomib using crystalline form M1 as a starting material. The present disclosure also relates to an improved process for the preparation of carfilzomib.