MASS SPECTROMETRY ANALYTE DETECTION AND RELATED METHODS

MASS SPECTROMETRY ANALYTE DETECTION AND RELATED METHODS

Processes and methods for modeling non-linear calibration behavior resulting from isotopic interference between a target analyte and an internal standard during a mass spectrometry operation are disclosed and described. In some embodiments, a correction to instrument data obtained during the mass sp...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rule, Geoffrey S, Yue, Bingfang, Clark, Zlatuse D, Rockwood, Alan L
Format: Patent
Sprache:eng
Schlagworte:
BASIC ELECTRIC ELEMENTS
ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
ELECTRICITY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Processes and methods for modeling non-linear calibration behavior resulting from isotopic interference between a target analyte and an internal standard during a mass spectrometry operation are disclosed and described. In some embodiments, a correction to instrument data obtained during the mass spectrometry operation can be made. Such a correction may entail determining, in some cases experimentally determining, one or two constants, and a single adjustable parameter for each analyte/internal standard pair.