Antibiotic Compounds, Pharmaceutical Formulations Thereof And Methods And Uses Therefor

Antibiotic Compounds, Pharmaceutical Formulations Thereof And Methods And Uses Therefor

The present invention relates to compounds of formula (I) wherein G1 to G8 are as defined herein. The compounds are PK inhibitors and as such represent a new approach to treating pathogenic infections, including multidrug resistant pathogens. Disclosed herein are the compounds of formula (I), pharma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tan, Jason Samuel, Mandel, Alexander Laurence, Jaquith, James Brian, Dullaghan, Edith Mary, Young, Robert Norman, Shidmoossavee, Fahimeh S, Hsieh, Tom Han Hsiao, Kumar, Nag Sharwan
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to compounds of formula (I) wherein G1 to G8 are as defined herein. The compounds are PK inhibitors and as such represent a new approach to treating pathogenic infections, including multidrug resistant pathogens. Disclosed herein are the compounds of formula (I), pharmaceutical compositions comprising the compounds of formula (I) and their use in the treatment of antimicrobial infection. (Formula (1))