COMPOSITION FOR PREVENTING AND TREATING INFLAMMATORY BOWEL DISEASE

Provided is a pharmaceutical composition for preventing or treating inflammatory bowel disease (IBD) comprising a mixed extract of at least two of Aucklandia lappa Decne, Terminalia chebula Retzius, and Zingiber officinale Rosc. as an active ingredient and a method thereof, and more specifically, to...

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Hauptverfasser: JUNG, Ju-ri, KIM, Ye Jin, CHO, Yong-baik, UM, Young-ran, JEON, Hyo Jin, SEO, Chae Shin, KIM, Seul-ki, KOO, Bon Am, MOK, So-youn, SHIN, Jae-hyuck, CHO, Hong Koo, KIM, Sang-Back, CHOI, Han-Seok, LIM, Soon-min
Format: Patent
Sprache:eng
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Zusammenfassung:Provided is a pharmaceutical composition for preventing or treating inflammatory bowel disease (IBD) comprising a mixed extract of at least two of Aucklandia lappa Decne, Terminalia chebula Retzius, and Zingiber officinale Rosc. as an active ingredient and a method thereof, and more specifically, to a pharmaceutical composition having an inhibitory effect on monocyte adhesion in intestinal epithelial cells, an effect of inhibiting the production of inflammatory cytokines, an effect of ameliorating colitis in an animal model of dextran sodium sulfate (DSS)-induced colitis, and an effect of ameliorating Crohn's disease in an animal model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced Crohn's disease.