SEQUESTRANTS OF ADVANCED GLYCATION END PRODUCT (AGE) PRECURSORS

Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals...

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Hauptverfasser: Holmes-Farley, Stephen Randall, Dhal, Pradeep K, Miller, Robert J, Besev, Magnus, Papoulis, Andrew T
Format: Patent
Sprache:eng
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Zusammenfassung:Sequestrants of AGE precursors comprise amines separated by 2, 3 or 4 carbons. Sequestrants of AGE precursors can be used as pharmaceutical agents and in pharmaceutical compositions. The sequestrants of AGE precursors are particularly useful binding AGE precursors and dietary dicarbonyls in mammals in the gastrointestinal tract for the treatment of ailments such as diabetic nephropathy, chronic renal disease, atherosclerosis, stroke, cataracts, and Alzheimer's disease.