METHOD FOR DETECTING Ppargc1a GENE SENSITIVE TO HIGH-LEVEL IONIZING RADIATION

A method for detecting genes sensitive to high-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to high-level ionizing radiation discovered in a carcinogenic entity and verified in a normal entity are detected, by subjecting a cancerous AKR/J mouse and a...

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Hauptverfasser: SHIN, Seok Cheol, KIM, Hee Sun, CHOI, Seung Jin, CHOI, Moo Hyun, BONG, Jin Jong
Format: Patent
Sprache:eng
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Zusammenfassung:A method for detecting genes sensitive to high-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to high-level ionizing radiation discovered in a carcinogenic entity and verified in a normal entity are detected, by subjecting a cancerous AKR/J mouse and a normal ICR mouse to high-level radiation. Thymus is collected therefrom and fatty acid metabolism-related genes are classified via microarray processing of the thymus. The genes are amplified and the levels of gene expression are measured. Thus, the present invention allows a gene having a specific reaction to radiation to be accurately detected by preventing the interference of confounding variables.