SUBCUTANEOUS RESERVOIR DEVICE AND METHOD OF MANUFACTURE

The medical devices of the present disclosure are filled reservoirs such as a cylinder comprised of a polymer film which contains a reservoir of active agent, plus excipient, in some cases, for disease prevention, treatment, and/or contraception. The polymer film is permeable to the active agent aft...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kleiman, Mark E, Rothrock, Ginger Denison, Johnson, Leah, Swarner, Stephanie Lynn, Durham, Phillip Gregory, Praino, JR., Robert F, Ponthoz, Ariane van der Straten
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The medical devices of the present disclosure are filled reservoirs such as a cylinder comprised of a polymer film which contains a reservoir of active agent, plus excipient, in some cases, for disease prevention, treatment, and/or contraception. The polymer film is permeable to the active agent after subcutaneous implantation of the device into a body. The cylinder is comprised by the lamination of one or two polymer films which are ultrasonically welded to contain the drug material. The use of an ultrasonic welding process enables sealing of the polymer films to create the closed cylinder. The medical device is useful for long term disease prevention, such as prevention of HIV infection.