PHTHALAZINONE DERIVATIVES

Compounds of the formula (I):wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X═NRX then n is 1 or 2 and if X═CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocycl...

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Bibliographische Detailangaben
Hauptverfasser:	Matthews, Ian Timothy Williams, Smith, Graeme Cameron, Cockcroft, Xiao-Ling Fan, Menear, Keith Allan, Loh, Vincent Junior M, Martin, Niall Morrison Barr, Kerrigan, Frank, Ashworth, Alan, Jackson, Stephen Philip
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY ELECTROTHERAPY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MAGNETOTHERAPY MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES RADIATION THERAPY ULTRASOUND THERAPY
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Beschreibung
Zusammenfassung:	Compounds of the formula (I):wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X═NRX then n is 1 or 2 and if X═CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.