ANTI-GITR ANTIBODIES FOR CANCER DIAGNOSTICS

Provided herein are diagnostic antibodies that bind to glucocorticoid-induced tumor necrosis factor receptor (GITR). Such antibodies are useful for methods of detecting the expression of GITR in biological samples, for example, tumor tissue, and identifying a cancer patient likely to respond to anti...

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Hauptverfasser: HAN, Michelle Minhua, KORMAN, Alan J, SELBY, Mark J, WANG, Changyu, LI, Huiming, CHAKRABORTY, Indrani, LEWIN, Anne C, LONBERG, Nils, SRINIVASAN, Mohan, WANG, Xi-Tao, HUANG, Haichun, HUANG, Richard Y, CHEN, Guodong, WONG, Susan Chien-Szu, ADELAKUN, Olufemi A, HENNING, Karla A
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein are diagnostic antibodies that bind to glucocorticoid-induced tumor necrosis factor receptor (GITR). Such antibodies are useful for methods of detecting the expression of GITR in biological samples, for example, tumor tissue, and identifying a cancer patient likely to respond to anti-GITR immunotherapy or predicting whether a cancer patient will respond to anti-GITR immunotherapy.