DRUG COMBINATION PREDICTION SYSTEM AND DRUG COMBINATION PREDICTION METHOD
A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be...
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creator | LU, Tzu-Pin CHUANG, Eric Y HSIAO, Hui-I TSAI, Mong-Hsun LIU, Wei-I LAI, Liang-Chuan SYU, Joey Jen-Hui HSIEH, Chia-Shan CHIU, Yu-Shian |
description | A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be a first interaction gene set; calculating a gene amount of the first interaction gene set to obtain a first interaction gene amount, and calculating a first percentage generated by the first interaction gene amount in the first original gene set; calculating an interaction value of the combination of the first drug and the second drug according to the first percentage; and selecting at least one synergistic pharmaceutical composition according to the interaction value. |
format | Patent |
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CHUANG, Eric Y ; HSIAO, Hui-I ; TSAI, Mong-Hsun ; LIU, Wei-I ; LAI, Liang-Chuan ; SYU, Joey Jen-Hui ; HSIEH, Chia-Shan ; CHIU, Yu-Shian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2018144098A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2018</creationdate><topic>CALCULATING</topic><topic>COMPUTING</topic><topic>COUNTING</topic><topic>ELECTRIC DIGITAL DATA PROCESSING</topic><topic>INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS</topic><topic>PHYSICS</topic><toplevel>online_resources</toplevel><creatorcontrib>LU, Tzu-Pin</creatorcontrib><creatorcontrib>CHUANG, Eric Y</creatorcontrib><creatorcontrib>HSIAO, Hui-I</creatorcontrib><creatorcontrib>TSAI, Mong-Hsun</creatorcontrib><creatorcontrib>LIU, Wei-I</creatorcontrib><creatorcontrib>LAI, Liang-Chuan</creatorcontrib><creatorcontrib>SYU, Joey Jen-Hui</creatorcontrib><creatorcontrib>HSIEH, Chia-Shan</creatorcontrib><creatorcontrib>CHIU, Yu-Shian</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LU, Tzu-Pin</au><au>CHUANG, Eric Y</au><au>HSIAO, Hui-I</au><au>TSAI, Mong-Hsun</au><au>LIU, Wei-I</au><au>LAI, Liang-Chuan</au><au>SYU, Joey Jen-Hui</au><au>HSIEH, Chia-Shan</au><au>CHIU, Yu-Shian</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DRUG COMBINATION PREDICTION SYSTEM AND DRUG COMBINATION PREDICTION METHOD</title><date>2018-05-24</date><risdate>2018</risdate><abstract>A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be a first interaction gene set; calculating a gene amount of the first interaction gene set to obtain a first interaction gene amount, and calculating a first percentage generated by the first interaction gene amount in the first original gene set; calculating an interaction value of the combination of the first drug and the second drug according to the first percentage; and selecting at least one synergistic pharmaceutical composition according to the interaction value.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CALCULATING COMPUTING COUNTING ELECTRIC DIGITAL DATA PROCESSING INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS PHYSICS |
title | DRUG COMBINATION PREDICTION SYSTEM AND DRUG COMBINATION PREDICTION METHOD |
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