DRUG COMBINATION PREDICTION SYSTEM AND DRUG COMBINATION PREDICTION METHOD

DRUG COMBINATION PREDICTION SYSTEM AND DRUG COMBINATION PREDICTION METHOD

A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LU, Tzu-Pin, CHUANG, Eric Y, HSIAO, Hui-I, TSAI, Mong-Hsun, LIU, Wei-I, LAI, Liang-Chuan, SYU, Joey Jen-Hui, HSIEH, Chia-Shan, CHIU, Yu-Shian
Format: Patent
Sprache:eng
Schlagworte:
CALCULATING
COMPUTING
COUNTING
ELECTRIC DIGITAL DATA PROCESSING
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
PHYSICS
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Beschreibung
Zusammenfassung:A drug combination prediction method comprising: storing a plurality of original gene sets, at least one first gene impacted by a first drug and at least one second gene impacted by a second drug; determining the part of the at least one first gene and the part of the at least one second gene to be a first interaction gene set; calculating a gene amount of the first interaction gene set to obtain a first interaction gene amount, and calculating a first percentage generated by the first interaction gene amount in the first original gene set; calculating an interaction value of the combination of the first drug and the second drug according to the first percentage; and selecting at least one synergistic pharmaceutical composition according to the interaction value.