Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV

Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV

Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.

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Bibliographische Detailangaben
Hauptverfasser: Ormerod Dominic John, Hermant Sébastien Nicolas J, Moody Thomas Shaw, Depré Dominique Paul Michel, Vriamont Nicolas, Brossat Maude, Riant Olivier, Lemaire Sébastien Francois Emmanuel, Horvath Andras
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Disclosed is a process for the preparation of certain intermediates, e.g. those in the scheme below: which intermediates and processes are useful in the preparation of the macrocyclic HVC inhibitor Simeprevir.