HANDHELD DEVICE AND MULTIMODAL CONTRAST AGENT FOR EARLY DETECTION OF HUMAN DISEASE

Systems comprising a combination of the handheld imaging system with a nanoparticle multimodal contrast agent are disclosed. The imaging system exploits the advantages of both near-infrared emission and the photoacoustic effect by employing calcium phosphosilicate nanocolloid that encapsulates NIR a...

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Bibliographische Detailangaben
Hauptverfasser:	TANG XIAOMENG, LOC WELLEY S, KESTER MARK, KNECHT SEAN D, ADAIR BERNADETTE M, TUTWILER RICHARD L, CHENG KEITH, SINOWAY LAWRENCE, ADAIR JAMES H, NEUBERGER THOMAS, CARR CONNOR, WILCZYNSKI ZACHARY R, BOYER J. ERIC, MATTERS GAIL L, MCGOVERN CHRISTOPHER
Format:	Patent
Sprache:	eng
Schlagworte:	DIAGNOSIS HUMAN NECESSITIES HYGIENE IDENTIFICATION MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SURGERY
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Beschreibung
Zusammenfassung:	Systems comprising a combination of the handheld imaging system with a nanoparticle multimodal contrast agent are disclosed. The imaging system exploits the advantages of both near-infrared emission and the photoacoustic effect by employing calcium phosphosilicate nanocolloid that encapsulates NIR and CT/MRI contrast agents for enhanced deep tissue imaging as well as a portable NIR/PA system using a tunable pulsed laser, CCD imaging technology and acoustic transducer arrays. Methods for using the system, for example in rapid diagnosis of trauma such as that inflicted on a battlefield, are provided.