INCREASED ETHANOL PRODUCTION BY THERMOPHILIC MICROORGANISMS WITH DELETION OF INDIVIDUAL HFS HYDROGENASE SUBUNITS

Disclosed are methods for engineering bacteria, for example, Thermoanaerobacterium saccharolyticum, that convert biomass to ethanol at high yield by deleting a single gene. Deletion of subunit A or subunit B of the hfs hydrogenase, but not deletion of subunit C or subunit D, results in an increase i...

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Hauptverfasser: Lynd Lee R, Olson Daniel G, Eminoglu Aysenur
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creator Lynd Lee R
Olson Daniel G
Eminoglu Aysenur
description Disclosed are methods for engineering bacteria, for example, Thermoanaerobacterium saccharolyticum, that convert biomass to ethanol at high yield by deleting a single gene. Deletion of subunit A or subunit B of the hfs hydrogenase, but not deletion of subunit C or subunit D, results in an increase in ethanol yield.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title INCREASED ETHANOL PRODUCTION BY THERMOPHILIC MICROORGANISMS WITH DELETION OF INDIVIDUAL HFS HYDROGENASE SUBUNITS
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