ANTIBODIES TO L-TYPE VOLTAGE GATED CHANNELS AND RELATED METHODS

Provided are antibodies, and antigen-binding fragments thereof, which specifically bind to an extracellular poor loop of an alpha 1a subunit of L-type voltage gated calcium channel, and related compositions, kits, and methods of use thereof, for instance, administration to a subject in need thereof...

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Bibliographische Detailangaben
Hauptverfasser: Munro Lonna, Fenninger Franz, Eyford Brett Alexander, Pfeifer Cheryl Gurine, Jefferies Wilfred Arthur, Gabathuler Reinhard, Choi Kyung Bok, Stanwood Shawna Rose
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided are antibodies, and antigen-binding fragments thereof, which specifically bind to an extracellular poor loop of an alpha 1a subunit of L-type voltage gated calcium channel, and related compositions, kits, and methods of use thereof, for instance, administration to a subject in need thereof to modify an immune response, for example, in the treatment of cancer.