Factor IXa Inhibitors

The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, th...

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Hauptverfasser: Li Hong, Ruiz Manuel de Lera, Parker, Jr. Dann L, Meng Dongfang, Yang Meng, Wu Jane Yang, Xu Jiayi, Orr Robert K, Zhang Ting, Dewnani Sunita V, Walsh Shawn P, Harper Bart, Campeau Louis-Charles, Wood Harold B, Berger Richard, Jian Tianying
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creator Li Hong
Ruiz Manuel de Lera
Parker, Jr. Dann L
Meng Dongfang
Yang Meng
Wu Jane Yang
Xu Jiayi
Orr Robert K
Zhang Ting
Dewnani Sunita V
Walsh Shawn P
Harper Bart
Campeau Louis-Charles
Wood Harold B
Berger Richard
Jian Tianying
description The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.
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The compounds are selective Factor IXa inhibitors.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20180125&amp;DB=EPODOC&amp;CC=US&amp;NR=2018022747A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20180125&amp;DB=EPODOC&amp;CC=US&amp;NR=2018022747A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Li Hong</creatorcontrib><creatorcontrib>Ruiz Manuel de Lera</creatorcontrib><creatorcontrib>Parker, Jr. Dann L</creatorcontrib><creatorcontrib>Meng Dongfang</creatorcontrib><creatorcontrib>Yang Meng</creatorcontrib><creatorcontrib>Wu Jane Yang</creatorcontrib><creatorcontrib>Xu Jiayi</creatorcontrib><creatorcontrib>Orr Robert K</creatorcontrib><creatorcontrib>Zhang Ting</creatorcontrib><creatorcontrib>Dewnani Sunita V</creatorcontrib><creatorcontrib>Walsh Shawn P</creatorcontrib><creatorcontrib>Harper Bart</creatorcontrib><creatorcontrib>Campeau Louis-Charles</creatorcontrib><creatorcontrib>Wood Harold B</creatorcontrib><creatorcontrib>Berger Richard</creatorcontrib><creatorcontrib>Jian Tianying</creatorcontrib><title>Factor IXa Inhibitors</title><description>The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. 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The compounds are selective Factor IXa inhibitors.</abstract><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Factor IXa Inhibitors
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