Factor IXa Inhibitors
The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, th...
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creator | Li Hong Ruiz Manuel de Lera Parker, Jr. Dann L Meng Dongfang Yang Meng Wu Jane Yang Xu Jiayi Orr Robert K Zhang Ting Dewnani Sunita V Walsh Shawn P Harper Bart Campeau Louis-Charles Wood Harold B Berger Richard Jian Tianying |
description | The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors. |
format | Patent |
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The compounds are selective Factor IXa inhibitors.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180125&DB=EPODOC&CC=US&NR=2018022747A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180125&DB=EPODOC&CC=US&NR=2018022747A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Li Hong</creatorcontrib><creatorcontrib>Ruiz Manuel de Lera</creatorcontrib><creatorcontrib>Parker, Jr. Dann L</creatorcontrib><creatorcontrib>Meng Dongfang</creatorcontrib><creatorcontrib>Yang Meng</creatorcontrib><creatorcontrib>Wu Jane Yang</creatorcontrib><creatorcontrib>Xu Jiayi</creatorcontrib><creatorcontrib>Orr Robert K</creatorcontrib><creatorcontrib>Zhang Ting</creatorcontrib><creatorcontrib>Dewnani Sunita V</creatorcontrib><creatorcontrib>Walsh Shawn P</creatorcontrib><creatorcontrib>Harper Bart</creatorcontrib><creatorcontrib>Campeau Louis-Charles</creatorcontrib><creatorcontrib>Wood Harold B</creatorcontrib><creatorcontrib>Berger Richard</creatorcontrib><creatorcontrib>Jian Tianying</creatorcontrib><title>Factor IXa Inhibitors</title><description>The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBB1S0wuyS9S8IxIVPDMy8hMygTyinkYWNMSc4pTeaE0N4Oym2uIs4duakF-fGpxQWJyal5qSXxosJGBoYWBkZG5ibmjoTFxqgDO4yGu</recordid><startdate>20180125</startdate><enddate>20180125</enddate><creator>Li Hong</creator><creator>Ruiz Manuel de Lera</creator><creator>Parker, Jr. Dann L</creator><creator>Meng Dongfang</creator><creator>Yang Meng</creator><creator>Wu Jane Yang</creator><creator>Xu Jiayi</creator><creator>Orr Robert K</creator><creator>Zhang Ting</creator><creator>Dewnani Sunita V</creator><creator>Walsh Shawn P</creator><creator>Harper Bart</creator><creator>Campeau Louis-Charles</creator><creator>Wood Harold B</creator><creator>Berger Richard</creator><creator>Jian Tianying</creator><scope>EVB</scope></search><sort><creationdate>20180125</creationdate><title>Factor IXa Inhibitors</title><author>Li Hong ; Ruiz Manuel de Lera ; Parker, Jr. Dann L ; Meng Dongfang ; Yang Meng ; Wu Jane Yang ; Xu Jiayi ; Orr Robert K ; Zhang Ting ; Dewnani Sunita V ; Walsh Shawn P ; Harper Bart ; Campeau Louis-Charles ; Wood Harold B ; Berger Richard ; Jian Tianying</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2018022747A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2018</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>Li Hong</creatorcontrib><creatorcontrib>Ruiz Manuel de Lera</creatorcontrib><creatorcontrib>Parker, Jr. Dann L</creatorcontrib><creatorcontrib>Meng Dongfang</creatorcontrib><creatorcontrib>Yang Meng</creatorcontrib><creatorcontrib>Wu Jane Yang</creatorcontrib><creatorcontrib>Xu Jiayi</creatorcontrib><creatorcontrib>Orr Robert K</creatorcontrib><creatorcontrib>Zhang Ting</creatorcontrib><creatorcontrib>Dewnani Sunita V</creatorcontrib><creatorcontrib>Walsh Shawn P</creatorcontrib><creatorcontrib>Harper Bart</creatorcontrib><creatorcontrib>Campeau Louis-Charles</creatorcontrib><creatorcontrib>Wood Harold B</creatorcontrib><creatorcontrib>Berger Richard</creatorcontrib><creatorcontrib>Jian Tianying</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Li Hong</au><au>Ruiz Manuel de Lera</au><au>Parker, Jr. Dann L</au><au>Meng Dongfang</au><au>Yang Meng</au><au>Wu Jane Yang</au><au>Xu Jiayi</au><au>Orr Robert K</au><au>Zhang Ting</au><au>Dewnani Sunita V</au><au>Walsh Shawn P</au><au>Harper Bart</au><au>Campeau Louis-Charles</au><au>Wood Harold B</au><au>Berger Richard</au><au>Jian Tianying</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Factor IXa Inhibitors</title><date>2018-01-25</date><risdate>2018</risdate><abstract>The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | Factor IXa Inhibitors |
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