Factor IXa Inhibitors

The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, th...

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Bibliographische Detailangaben
Hauptverfasser:	Li Hong, Ruiz Manuel de Lera, Parker, Jr. Dann L, Meng Dongfang, Yang Meng, Wu Jane Yang, Xu Jiayi, Orr Robert K, Zhang Ting, Dewnani Sunita V, Walsh Shawn P, Harper Bart, Campeau Louis-Charles, Wood Harold B, Berger Richard, Jian Tianying
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.