ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE

The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates. The invention further provides methods for using the conjugates to deliver the active agent to a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim Sun Young, Chung Yunseo, Oh Kyu Man, Park Yun Hee, Kwon Hyun Jin, Jung Doo Hwan, Woo Sung Ho, Lee Hyang Sook, Park Tae Kyo, Kim Youngun, Kim Yong Zu, Cho Jong Un
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent)