CHEMICAL MODEL OF A NEURODEGENERATIVE DISEASE, METHOD FOR PREPARATION AND USES OF SAME

CHEMICAL MODEL OF A NEURODEGENERATIVE DISEASE, METHOD FOR PREPARATION AND USES OF SAME

The invention concerns the use of pyridinium furosemide or one of the derivatives, analogues, salts, metabolites, or prodrugs thereof in the preparation of a chemical model of a neurodegenerative disease, preferably Parkinson's disease. The invention also concerns the corresponding chemical mod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RIVARD MICHAEL, LEHRI-BOUFALA SONIA, ZEGHBIB NARIMANE, LAURENCE CELINE, MORIN CHRISTOPHE, MARTENS THIERRY
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Beschreibung
Zusammenfassung:The invention concerns the use of pyridinium furosemide or one of the derivatives, analogues, salts, metabolites, or prodrugs thereof in the preparation of a chemical model of a neurodegenerative disease, preferably Parkinson's disease. The invention also concerns the corresponding chemical model and the uses of same, in particular in screening tests for identifying drug candidates.