EXTRACELLULAR VESICLES WITH ENHANCED POTENCY

Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions ass...

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Hauptverfasser: HOGAN Sarah, MEDRANO Carolina, ILAGAN Roger Marquez, RODRIGUEZ Maria Pia, CHEADLE John
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are methods for isolating potent extracellular vesicle or exosome populations from mesenchymal stromal cells, and the use of the isolated extracellular vesicles or exosomes in treating vasculopathy, including pulmonary hypertension, bronchopulmonary dysplasia, and disease and conditions associated with mitochondrial dysfunction.