DEVELOPMENT OF METHODS FOR PRODUCTION OF A WHOLE VIRUS VACCINE CANDIDATE STOCK AND NOVEL ADAPTIVE MUTATIONS IN HEPATITIS C VIRUS

The present invention relates to methods for obtaining a whole virus vaccine candidate stock. The present invention also relates to an inactivated whole virus vaccine candidate stock that can be used for vaccination purposes as well as development of novel high titer virus, which is the preferred vi...

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Hauptverfasser: Jensen Tanja Bertelsen, Bukh Jens, Mathiesen Christian Kjærulff, Gottwein Judith Margarete
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to methods for obtaining a whole virus vaccine candidate stock. The present invention also relates to an inactivated whole virus vaccine candidate stock that can be used for vaccination purposes as well as development of novel high titer virus, which is the preferred virus for this technique.